» Hope For Effective Endometriosis Screening Following Gene Mutation Discovery
08/02/12 09:00 from Pain News From Medical News Today
Researchers at Yale School of Medicine have, for the first time, described the genetic basis of endometriosis, a condition affecting millions of women that is marked by chronic pelvic pain and infertility. The researchers\' discovery of a ne..
» Painful Periods Eased By Combined Oral Contraceptive Pill
08/02/12 09:00 from Pain News From Medical News Today
A large Scandinavian study, that has been running for 30 years, has finally provided convincing evidence that the combined oral contraceptive pill does, indeed, alleviate the symptoms of painful menstrual periods reports scientists from the..
» How To Boost The Power Of Pain Relief, Without Drugs
06/02/12 09:00 from Pain News From Medical News Today
Placebos reduce pain by creating an expectation of relief. Distraction - say, doing a puzzle - relieves it by keeping the brain busy. But do they use the same brain processes? Neuromaging suggests they do. When applying a placebo, s..
» Multiple Exposure To Anesthesia Increases Risk Of ADHD In Young Children
06/02/12 08:00 from Pain News From Medical News Today
Mayo Clinic researchers have found that multiple exposures to anesthesia at a young age are associated with higher rates of attention-deficit/hyperactivity disorder (ADHD). Children exposed to two or more anesthetics before age 3 had mo..
» Anesthesia Exposure Linked To ADHD In Children
03/02/12 08:00 from Pain News From Medical News Today
A study by researchers at Mayo Clinic, Rochester Minn., and published in Mayo Clinic Proceedings, reveals that children who have been under anesthesia many times when they are young have a greater risk of developing attention-deficit/h..
» Space Researchers Develop Ultrasound Technology That Detects, Treats Kidney Stones
02/02/12 09:00 from Pain News From Medical News Today
Just the mention of kidney stones can cause a person to cringe. They are often painful and sometimes difficult to remove, and 10 percent of the population will suffer from them. In space, the risk of developing kidney stones is exacerbated ..
» Helping Seniors With Pain: New GSA Resources
02/02/12 09:00 from Pain News From Medical News Today
The pain suffered by older adults is the shared focus of the two newest entries in The Gerontological Society of America\'s (GSA) From Publication to Practice* series. Together they address both pain management and new labeling changes for o..
» Massages Scientifically Proven To Help Reduce Pain
02/02/12 08:00 from Pain News From Medical News Today
According to a study published online in Science Translational Medicine by researchers from the Buck Institute for Research on Aging and McMaster University in Hamilton Ontario, massages aid the growth of new mitochondria in skeletal muscl..
» Researchers Develop Novel Drug Delivery System
02/02/12 08:00 from Pain News From Medical News Today
Long duration, controllable drug delivery is of wide interest to medical researchers and clinicians, particularly those seeking to improve treatment for patients with chronic pain or to prevent cancer recurrence after surgery...
» New Drug Release Mechanism Developed That Utilizes 3D Superhydrophobic Materials
31/01/12 08:00 from Pain News From Medical News Today
According to a recent study, there is a new mechanism of drug release using 3D superhydrophobic materials that utilizes air as a removable barrier to control the rate at which drug is released. The study was electronically published in the ..
» Cyberknife Radiation Successful For Treating Tigeminal Neuralgia
30/01/12 17:00 from Pain News From Medical News Today
A small study published online in the Journal of NeuroInterventional Surgery shows that a technique in which highly concentrated beams of radiation are used, known as Cyberknife, can relieve the stabbing pain of the facial nerve condition t..
» Sedentary Lifestyle A Problem For 2 In 5 Adults With Rheumatoid Arthritis
27/01/12 09:00 from Pain News From Medical News Today
A new study, funded by a grant from the National Institute for Arthritis and Musculoskeletal and Skin Diseases (NIAMS), found that two in five adults (42%) with rheumatoid arthritis (RA) were inactive...
» What Is Achilles Tendon Inflammation? What Is Achilles Tendinitis?
27/01/12 08:00 from Pain News From Medical News Today
Achilles tendinitis (tendonitis) or Achilles tendon inflammation occurs when the Achilles tendon becomes inflamed as a result of the Achilles tendon being put under too much strain. The Achilles tendon joins the calf muscles to the heel bon..
» Recommendations For Tablet Computer Use To Avoid Shoulder Pain
26/01/12 08:00 from Pain News From Medical News Today
The sudden popularity of tablet computers such as the Apple iPad® has not allowed for the development of guidelines to optimize users\' comfort and well-being...
» Muscle Soreness Quantified By Researchers
25/01/12 09:00 from Pain News From Medical News Today
Quantifying how sore a person is after a long workout is a challenge for doctors and researchers, but scientists from Loma Linda and Asuza Pacific Universities think they may have figured it out. Their research article describing a new tech..
» Study Of Electronic Medical Records Reveals That Women Report Feeling Pain More Intensely Than Men
25/01/12 08:00 from Pain News From Medical News Today
Women report more-intense pain than men in virtually every disease category, according to Stanford University School of Medicine investigators who mined a huge collection of electronic medical records to establish the broad gender diffe..
» Females More Sensitive To Pain Than Males? Possibly
23/01/12 21:00 from Pain News From Medical News Today
The idea that men suffer more when in pain than women could well be a myth, according to a new report written by Stanford University researchers in the Journal of Pain. The authors say that their large study found that even though women are..
» Research Scientists Provide New Understanding Of Chronic Pain
23/01/12 09:00 from Pain News From Medical News Today
Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective...
» Major Public Health Campaign Called For By Stanford Dean To Fight Epidemic Of Unnecessary Suffering
20/01/12 09:00 from Pain News From Medical News Today
The amount of needless suffering caused by both acute and chronic pain in the United States is a major, overlooked medical problem that requires improved education at multiple levels, stretching from the implementation of new public health ..
» Aspirin Merits Testing For Prevention Of Cervical Cancer In HIV-Infected Women
20/01/12 09:00 from Pain News From Medical News Today
Research conducted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center global health investigators and cancer specialists in New York, Qatar and Haiti suggests that aspirin should be evaluated for its ability to prevent develo..
» Study Finds Good Intentions Ease Pain, Add To Pleasure
20/01/12 09:00 from Pain News From Medical News Today
A nurse\'s tender loving care really does ease the pain of a medical procedure, and grandma\'s cookies really do taste better, if we perceive them to be made with love - suggests newly published research by a University of Maryland psycho..
» Extended Pain Relief For Laser Eye Surgery Patients Via Contact Lenses
20/01/12 08:00 from Pain News From Medical News Today
Scientists are reporting development of contact lenses that could provide a continuous supply of anesthetic medication to the eyes of patients who undergo laser eye surgery - an advance that could relieve patients of the burden of repea..
» Painful Period Symptoms Reduced By Oral Contraceptive Pill
19/01/12 16:00 from Pain News From Medical News Today
â¨In the United States, painful periods (Dysmenorrhoea) are estimated to cause 600 million lost working hours and cost two billion dollars in lost productivity...
» Managing Rheumatoid Arthritis Pain With Muscle Relaxants And Neuromodulators
19/01/12 08:00 from Pain News From Medical News Today
Pain management is a high priority for patients with rheumatoid arthritis, so three researchers in Australia analysed existing study data to see whether two different classes of drugs can help. When looking at muscle relaxants, they discove..
» Do Herbal Meds Help Osteoarthritis? Probably Not
16/01/12 18:00 from Pain News From Medical News Today
A comprehensive review of herbal medicine products in the latest issue of the Drug and Therapeutics Bulletin (DTB) shows that there is little conclusive evidence to justify the widespread use of herbal medicines to relieve the symptoms of t..
» The Relationship Between Preoperative and Primary Care Blood Pressure Among Veterans Presenting from Home for Surgery: Is There Evidence for Anesthesiologist-Initiated Blood Pressure Referral? [ECONOMICS, EDUCATION, AND POLICY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: American College of Cardiology/American Heart Association guidelines describe the perioperative evaluation as \"a unique opportunity to identify patients with hypertension\"; however, factors such as anticipatory stress or medica..
» Salvinorin A Pretreatment Preserves Cerebrovascular Autoregulation After Brain Hypoxic/Ischemic Injury via Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase in Piglets [NEUROSCIENCE IN ANESTHESIOLOGY AND PERIOPERATIVE MEDICINE]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Cerebral hypoxia/ischemia during infant congenital heart surgery is not uncommon and may induce devastating neurologic disabilities persistent over the lifespan. Hypoxia/ischemia-induced cerebrovascular dysfunction is thought t..
» Cardiovascular Effects of Dexmedetomidine Sedation in Children [PEDIATRIC ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Dexmedetomidine (DEX) affects heart rate (HR), mean arterial blood pressure, cardiac index (CI), stroke index (SI), and systemic vascular resistance index (SVRI) in adults. In this study we sought to determine whether similar e..
» Focused Review: Simulation in Obstetric Anesthesia [OBSTETRIC ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
Simulation can be used to teach technical skills, to evaluate clinician performance, to help assess the safety of the environment of care, and to improve teamwork. Each of these has been successfully demonstrated in obstetric anesthesia si..
» Ropivacaine Continuous Wound Infusion Versus Epidural Morphine for Postoperative Analgesia After Cesarean Delivery: A Randomized Controlled Trial [OBSTETRIC ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: The infusion of local anesthetic in the surgical wound is helpful in the multimodal management of postoperative pain. We hypothesized that local anesthetic wound infusion after cesarean delivery would provide better pain contro..
» Fluid Resuscitation with 6% Hydroxyethyl Starch (130/0.4) in Acutely Ill Patients: An Updated Systematic Review and Meta-Analysis [CRITICAL CARE, TRAUMA, AND RESUSCITATION]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Recent research suggests that 6% hydroxyethyl starch (HES) 130/0.4 is one of the most frequently used resuscitation fluids worldwide. The retraction of studies evaluating its use necessitates a reevaluation of available evidenc..
» Intravenous Infusion of Remifentanil Induces Transient Withdrawal Hyperalgesia Depending on Administration Duration in Rats [ANALGESIA]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Recent studies suggest that remifentanil, similar to other μ-opioid agonists, may induce hyperalgesia. We performed animal experiments to determine whether IV remifentanil infusion, the mode of administration used in clinica..
» Racial and Ethnic Disparities in Neuraxial Labor Analgesia [OBSTETRIC ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Racial and ethnic disparities in the treatment of pain have been well documented, and there is evidence of such disparities in neuraxial analgesia use. Our objectives of this study were to analyze racial/ethnic disparities in n..
» Kaplan\'s Cardiac Anesthesia: The Echo Era, 6th ed., Expert Consult Premium Edition [BOOK, MULTIMEDIA, AND MEETING REVIEWS]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» The Essence of Analgesia and Analgesics [BOOK, MULTIMEDIA, AND MEETING REVIEWS]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Essence of Anesthesia Practice, 3rd ed. [BOOK, MULTIMEDIA, AND MEETING REVIEWS]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Brief Report: Plasma Ropivacaine Concentrations After Ultrasound-Guided Rectus Sheath Block in Patients Undergoing Lower Abdominal Surgery [ANALGESIA]
19/12/11 17:03 from Anesthesia & Analgesia current issue
A rectus sheath block can provide postoperative analgesia for midline incisions. However, information regarding the pharmacokinetics of local anesthetics used in this block is lacking. In this study, we detail the time course of ropivacain..
» Brief Report: A Comparison of an Injection Cephalad or Caudad to the Division of the Sciatic Nerve for Ultrasound-Guided Popliteal Block: A Prospective Randomized Study [ANALGESIA]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: The optimal site for local anesthetic injection during ultrasound-guided sciatic popliteal block remains controversial. METHODS: Patients were randomized to receive 25 mL ropivacaine 0.75% around the sciatic nerve cephalad to t..
» Brief Report: Ultrasound-Guided Obturator Nerve Block: A Proximal Interfascial Technique [ANALGESIA]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: In this report, I describe and evaluate a proximal ultrasound (US)-guided obturator nerve block technique using an interfascial local anesthetic (LA) injection deep to the pectineus muscle. METHODS: The pectineus muscle was ide..
» Normal Tp-e Values in Children [LETTERS TO THE EDITOR]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» In Response [LETTERS TO THE EDITOR]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Improving Surgical Outcome: Combine Evidence from Unimodal Interventions [LETTERS TO THE EDITOR]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Failure to Cycle Noninvasive Blood Pressure Cuff After Anesthesia Monitor Upgrade [LETTERS TO THE EDITOR]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» The Differential Effect of Intrathecal Nav1.8 Blockers on the Induction and Maintenance of Capsaicin- and Peripheral Ischemia-Induced Mechanical Allodynia and Thermal Hyperalgesia [ANALGESIA]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: It has been reported that the selective blockade of Nav1.8 sodium channels could be a possible target for the development of analgesics without unwanted side effects. However, the precise role of spinal Nav1.8 in the induction ..
» Silicon Jubilee [EDITORIALS]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Special Article: Guidelines for Performing Ultrasound Guided Vascular Cannulation: Recommendations of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists [CARDIOVASCULAR ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» A Single Injection of Botulinum Toxin Decreases the Margin of Safety of Neurotransmission at Local and Distant Sites [ANESTHETIC PHARMACOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: We tested the hypothesis that a single injection of botulinum toxin not only has local, but also distant effects on muscle function, biochemistry, and pharmacodynamics of atracurium. METHODS: Botulinum toxin (2.5 U) was injecte..
» The Involvement of Adenosine Triphosphate-Sensitive Potassium Channels in the Different Effects of Sevoflurane and Propofol on Glucose Metabolism in Fed Rats [ANESTHETIC PHARMACOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Recently, we reported marked differences in the effects of sevoflurane and propofol on glucose metabolism; glucose use is impaired by sevoflurane, but not by propofol. Opening of adenosine triphosphate-sensitive potassium chann..
» ED50 and Recovery Times After Propofol in Rats with Graded Cirrhosis [ANESTHETIC PHARMACOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Patients with end-stage liver disease have increased sensitivity to general anesthetics. In this study, we sought to quantify sensitivity to propofol as a function of the degree of liver disease, in a rat model of cirrhosis. ME..
» Opioid Binding Sites in Human Serum Albumin [ANESTHETIC PHARMACOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Human serum albumin (HSA) is an important carrier for opioids. However, the locations of the binding sites remain unclear. In the present study, we have characterized opioid–HSA interactions using multiple biochemical and..
» Review Article: Closed-Loop Systems in Anesthesia: Is There a Potential for Closed-Loop Fluid Management and Hemodynamic Optimization? [TECHNOLOGY, COMPUTING, AND SIMULATION]
19/12/11 17:03 from Anesthesia & Analgesia current issue
Closed-loop (automated) controllers are encountered in all aspects of modern life in applications ranging from air-conditioning to spaceflight. Although these systems are virtually ubiquitous, they are infrequently used in anesthesiology b..
» Case Report: Automated Machine Checkout Leaves an Internal Gas Leak Undetected: The Need for Complete Checkout Procedures [TECHNOLOGY, COMPUTING, AND SIMULATION]
19/12/11 17:03 from Anesthesia & Analgesia current issue
We report a complete internal fresh gas flow disconnect within a Dräger Fabius GS anesthesia machine without any alarms being triggered. This was undetected primarily because of an incomplete machine checkout in which the step of ensu..
» The Epidemiology of Upper Airway Injury in Patients Undergoing Major Surgical Procedures [PATIENT SAFETY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: Airway injury is a potentially serious and costly adverse event of anesthesia care. The epidemiologic characteristics of airway injury have not been well documented. METHODS: The American College of Surgeons National Surgical Q..
» Special Article: Creation of a Guide for the Transfer of Care of the Malignant Hyperthermia Patient from Ambulatory Surgery Centers to Receiving Hospital Facilities [AMBULATORY ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
CLINICAL PROBLEM: Volatile anesthetics and/or succinylcholine may trigger a potentially lethal malignant hyperthermia (MH) event requiring critical care crisis management. If the MH triggering anesthetic is given in an ambulatory surgical ..
» Case Report: Separation from Cardiopulmonary Bypass with a Rigid Bronchoscope Airway After Hemoptysis and Bronchial Impaction with Clot [CARDIOVASCULAR ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
Hemoptysis after cardiopulmonary bypass (CPB) occasionally occurs, and has varying clinical significance based upon amount of bleeding. Hemoptysis resulting in a clot and airway obstruction is an extremely rare event found almost exclusive..
» The IARS in 2012 [EDITORIALS]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Education in Anesthesia: Then & Now [EDITORIALS]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Special Article: 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines [CARDIOVASCULAR ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Review Article: Unexpected Bleeding in the Operating Room: The Role of Acquired von Willebrand Disease [CARDIOVASCULAR ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
Acquired von Willebrand disease (AvWD) is a rare bleeding disorder that occurs in association with a variety of underlying disorders and can lead to unforeseen bleeding in surgical patients. Cardiovascular as well as malignant and immunolo..
» Echo Rounds: The Use of Transesophageal Echocardiography for Confirmation of Appropriate Impella 5.0 Device Placement [CARDIOVASCULAR ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Tracheal Intubation Through the I-gelTM Supraglottic Airway Versus the LMA FastrachTM: A Randomized Controlled Trial [PATIENT SAFETY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
BACKGROUND: The i-gel TM is a supraglottic airway device not requiring inflation of a cuff for lung ventilation. Its design allows for unobstructed passage of a tracheal tube and previous studies have demonstrated a favorable alignment wit..
» Echo Rounds: Aneurysm of the Anterior Mitral Valve [CARDIOVASCULAR ANESTHESIOLOGY]
19/12/11 17:03 from Anesthesia & Analgesia current issue
» Interference with BISTM values from a forced-air warming device
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Reply from the authors
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Increase in cerebral metabolites during induction of propofol anaesthesia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Anaemia tolerance: bridging with intravenous ferric carboxymaltose in a patient with acute post-haemorrhagic anaemia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Nebulized magnesium for prevention of postoperative sore throat
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Is age a predictor of mortality in a UK medical high dependency unit?
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Anaesthesia, Intensive Care and Pain Management for the Cancer Patient
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Pediatric Critical Care
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Oxford Handbook of Pain Management
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Acknowlegement of Assesors
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Ultrasound-guided supraclavicular approach to the subclavian vein in infants and children
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Minimal mortality benefit with early surgery for high-risk fractured hip patients
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Bibliometrics of anaesthesia researchers in the UK
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Remote measurement of the leak around the uncuffed tracheal tube: objective measurement and physical characteristics
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background We have developed a technique for measuring a characteristic of the tracheal tube (TT)–trachea interface: the leak conductance (LC). This study aimed to validate the technique in the laboratory and to compare LC with measu..
» Adding dexamethasone to peripheral nerve blocks can give better postoperative analgesia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Force and pressure distribution using Macintosh and GlideScope laryngoscopes in normal and difficult airways: a manikin study
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background The forces applied to the soft tissues of the upper airway may have a deleterious effect. This study was designed to evaluate the performance of the GlideScope compared with the Macintosh laryngoscope. Methods Twenty anaesthetis..
» Simulating face-to-face tracheal intubation of a trapped patient: a randomized comparison of the LMA Fastrach™, the GlideScope™, and the Airtraq™ laryngoscope
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background We undertook a prospective randomized comparison of the LMA Fastrach™, Airtraq™ laryngoscope, and GlideScope™ used for face-to-face tracheal intubation simulated to mimic an entrapped patient. Methods Thirty se..
» Simulated evaluation of a non-Luer safety connector system for use in neuraxial procedures
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Spinal syringes, needles, and other devices with connectors that will not also connect with Luer devices could substantially reduce wrong-route drug administration errors. This study aimed to evaluate a newly designed non-Luer s..
» Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Video-assisted thoracic surgery (VATS) lobectomy may potentially reduce the risk of post-thoracotomy pain syndrome (PTPS). However, it may still carry a risk of intraoperative nerve damage and thereby development of PTPS. Thus, ..
» Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Psychological factors are thought to drive inter-patient variations in anaesthetic and analgesic requirements. This cross-sectional study investigated whether preoperative psychological factors can predict anaesthetic requiremen..
» Suspected opioid-induced hyperalgesia in an infant
12/12/11 15:37 from British Journal of Anaesthesia - current issue
One explanation for diminished opioid analgesic efficacy is opioid-induced hyperalgesia (OIH). We report a case of OIH in an infant with gastroschisis, requiring multiple surgical interventions and prolonged sedation for ventilation. This ..
» Hydroxyethyl starch in patients with trauma
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Intraoperative use of transoesophageal Doppler to predict response to volume expansion in infants and neonates
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Volume expansion (VE) in neonates or infants during volatile anaesthesia may lead to fluid overload if inappropriate. Transoesophageal Doppler (TED), a non-invasive cardiac output monitoring technique, can provide a comprehensiv..
» National Institute of Academic Anaesthesia research priority setting exercise
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Formal research priority setting is a recognized way of identifying important clinical research questions and promoting these as topics for commissioned research. This paper describes a research priority setting exercise conduct..
» Randomized controlled trial of intraoperative goal-directed fluid therapy in aerobically fit and unfit patients having major colorectal surgery
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Intraoperative fluid therapy regimens using oesophageal Doppler monitoring (ODM) to optimize stroke volume (SV) (goal-directed fluid therapy, GDT) have been associated with a reduction in length of stay (LOS) and complication ra..
» Multicentre cohort study of red blood cell use for revision hip arthroplasty and factors associated with greater risk of allogeneic blood transfusion
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Revision hip arthroplasty (RHA) is associated with high rates of allogeneic blood transfusion (ABT). We aimed to determine factors associated with ABT in patients undergoing RHA in Scottish hospitals, with particular focus on pe..
» Randomized, prospective, observational simulation study comparing residents\' needle-guided vs free-hand ultrasound techniques for central venous catheter access
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Short-axis ultrasound-guided placement of central venous catheters (CVCs) is widely accepted as safe practice. However, utilizing the long-axis approach could further improve safety, as it allows for better visualization of the ..
» Prediction of fluid responsiveness in infants and neonates undergoing congenital heart surgery
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Dynamic variables reliably predict fluid responsiveness (FR) in adults, but no data are available regarding their performance in infants. The aim of this prospective study was to assess whether pulse pressure variation (PPV) and..
» aepEX monitor for the measurement of hypnotic depth in patients undergoing balanced xenon anaesthesia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Previously, we showed a significant difference in the measurements of hypnotic depth by the bispectral index (BIS) and auditory-evoked potentials (AEPs) using the A-line autoregressive index during xenon anaesthesia. In the pres..
» What comes first? The dynamics of cerebral oxygenation and blood flow in response to changes in arterial pressure and intracranial pressure after head injury
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Brain tissue partial oxygen pressure ( P bt O 2 ) and near-infrared spectroscopy (NIRS) are novel methods to evaluate cerebral oxygenation. We studied the response patterns of P bt O 2 , NIRS, and cerebral blood flow velocity (C..
» Comparison of thromboelastometry (ROTEM(R)) with standard plasmatic coagulation testing in paediatric surgery
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background Thromboelastometry (ROTEM ® ) might be useful to detect intraoperative coagulation disorders early in major paediatric surgery. This observational trial compares this technique to standard coagulation tests. Methods Intraope..
» In the January 2012 BJA ...
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Setting research priorities in anaesthesia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
» Paediatric cardiomyopathy and anaesthesia
12/12/11 15:37 from British Journal of Anaesthesia - current issue
‘Cardiomyopathy’ (CM) is defined by the World Health Organization as ‘a disease of the myocardium associated with cardiac dysfunction’. In a child, it is associated with a significant risk for anaesthesia. In additi..
» Adverse event reporting tool to standardize the reporting and tracking of adverse events during procedural sedation: a consensus document from the World SIVA International Sedation Task Force
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Currently, there are no established definitions or terminology for sedation-related adverse events (AEs). With clear terminology and definitions, sedation events may be accurately identified and tracked, providing a benchmark for defining ..
» Roles of neuronal nitric oxide synthase, oxidative stress, and propofol in N-methyl-D-aspartate-induced dilatation of cerebral arterioles
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background It remains unclear whether N -methyl- d -aspartate (NMDA) receptors contribute to cerebral parenchymal vasodilatation, and any effects of clinically used anaesthetics on the dilatation. The present study was designed to examine ..
» Validity of the 6 min walk test in prediction of the anaerobic threshold before major non-cardiac surgery
12/12/11 15:37 from British Journal of Anaesthesia - current issue
Background For perioperative risk stratification, a robust, practical test could be used where cardiopulmonary exercise testing (CPET) is unavailable. The aim of this study was to assess the utility of the 6 min walk test (6MWT) distance t..
» Table of Contents.
21/07/11 03:06 from Anesthesiology. Volume 108(3) March 2008
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